Germain Sée (February 6, 1818 – May 12, 1896) was a French clinician who was a native of Ribeauvillé, Haut-Rhin.
He studied medicine in Paris, and in 1846 obtained his doctorate with a dissertation on ergotism. In 1855 he became médecin des hôpitaux in Paris, and subsequently worked at La Rochefoucauld (1857), Beaujon (1861), Pitié (1862) and Charité (1868) hospitals. In 1867 he succeeded Armand Trousseau (1801–1867) as professor of therapeutics and materia medica, and in 1876 attained the chair of clinical medicine at the Hôtel-Dieu de Paris, a position he held for the remainder of his career.
Sée specialized in the study of lung and cardiovascular diseases, and made contributions involving research of chorea and its association with rheumatic disorders. He conducted extensive studies of various drugs, and was an advocate of antipyrine for headaches, and sodium salicylate for treatment of rheumatism.
Among his written works was the nine volume Médecine clinique that he co-authored with Frédéric Labadie-Lagrave (1844–1917), and Leçons de pathologie expérimentale, a treatise on experimental pathology that was edited and published by Maurice Raynaud (1834–1881). In 1869 he became a member of the Académie de Médecine.